Interactions With Benzodiazepines and Other CNS Depressants Advise patients and caregivers that potentially deadly additive effects might manifest if acetaminophen and codeine phosphate tablets are used with benzodiazepines or other CNS depressants, such as alcohol, rather than to employ these drugs concomitantly unless supervised by a healthcare company (see WARNINGS https://codeine.store/codeine-cough-syrup/