This review recounts the origins and development of the concept of the hypothalamic gonadotropin-releasing hormone (GnRH) pulse generator. It starts in the late 1960s when striking rhythmic episodes of luteinizing hormone secretion. as reflected by circulating concentrations of this gonadotropin. were first observed in monkeys and ends in the present day. https://www.emporiumsmokeshopstles.shop/product-category/pipe-pouches/